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SARMS / STEROIDS AND THE DIFFERENCE BETWEEN

Updated: Oct 19, 2020


What are SARMS?

Selective Androgen Receptor Modulators (SARMs) are a class of therapeutic compounds that have similar properties to anabolic agents, but with reduced androgenic properties. This property allows SARMs the advantage of androgen-receptor specificity, tissue selectivity, and the lack of steroid-related side effects. Some potential side effects of anabolic steroid use include acne, liver damage, breast tissue development, and shrinking of the testicle in males, and deepening of the voice, growth of hair on the face, stomach, upper back, and abnormal menstrual cycles in females. SARMs have the ability to differentiate between anabolic and androgenic activities, and this provides the potential for therapeutic opportunities in a variety of medical conditions including muscle-wasting diseases, osteoporosis, cancer, and hypogonadism.


  1. LGD 4033

  2. MK 677

  3. GW 501516

  4. RAD 140

  5. Ostarine


LGD 4033 :

LGD 4033 a S.A.R.M like Ostarine but 12 times as powerful at only 1/3 the dose! Consequently it is more suppressive to the HPTA (Hypothalamus-Pituitary-Testes-Axis – the system of the hypothalamus, pituitary gland and gonadal glands, which plays a vital role in the development and regulation of the reproductive and immune systems). So, a SERM (selective estrogen receptor modulator) post cycle therapy is recommended.


Where Ostarine is best used in a cutting cycle, LGD has proven itself as a good bulking agent. LGD has a half-life ranging between 24 and 36 hours so daily dosing is optimal.


MK 677 :

This is a non-peptidic, orally active and selective agonist of the growth hormone secretagogue (secretion-boosting) receptor. It mimics the action of ghrelin (the hormone that regulates appetite and the distribution and rate of use of energy) in the stomach, raising growth hormone and IGF-1 levels, but does not affect cortisol levels.


Human studies have shown it to increase both muscle mass and bone mineral density. Dosed at 25mg daily, Ibutamoren has been shown to increase IGF-1 levels by 60% in 6 weeks in humans. A 72% increase in IGF-1 levels was seen after 12 months.


MK 677 is non-hormonal and therefore requires no PCT after the cycle is over. It is best utilised in at least a 3 month cycle with dosage increasing each month. The optimal dosing time for MK 677 is at night directly before going to bed. You should start to notice a deeper sleep almost immediately. If you should wake up with numb or tingly hands, do not worry. This is a common side effect of the extra GH in the system.


GW 501516 :

This is actually not a S.A.R.M. In fact it is a PPAR Delta Modulator – a selective agonist with a high affinity for the PPAR (peroxisome proliferator-activated receptors - a group of steroid- and thyroid-sensing proteins that control the expression of genes, thereby regulating cellular development and metabolism). This modulation allows the body to utilise more glucose and create more muscle tissue. GW also regulates the various proteins that the body uses for energy. For the user, this means an increase in energy and endurance, and it may also mean an increase in muscle mass. It is also possible that GW might have a positive effect on blood pressure and lipid profile. Dosing is in the 7mg to 21mg range, with 14mg being the "sweet spot". The average GW cycle is typically 4 to 12 weeks. GW is non-hormonal and therefore requires no PCT. However, it does stack well with SARMS to further increase fat loss and endurance.



RAD 140 :

RAD 140 is very new, so there isn't a lot of real world data on it yet. However, it does look very promising, with an impressive anabolic to androgenic ratio of 90:1! This means that users can experience a wealth of muscle building effects without all the associated androgenic side effects. RAD is powerful enough to limit the effect of testosterone on the prostate and other unwanted areas. It has even been shown to be more anabolic than testosterone, as well. Dosing appears to be in the 4mg to 12mg range, with optimal cycle length being 4 to 6 weeks. Given its shorter half-life (16 hours), RAD needs to be dosed at least twice daily.



Ostarine :

This is probably the most well-known S.A.R.M. It is best used to preserve muscle mass while in a caloric deficit. Ostarine can and will suppress your natural testosterone production in longer, higher dosed cycles, so a SERM PCT is needed. Ostarine can also cause gyno in some users, so it is recommended that you have an AI, like Exemestane, on hand. The average cycle length is 6 to 10 weeks at a dosage range of 10mg to 25mg.

( Credit to the Reggie Johal )


Common Quenstion :

Are SARMs the same as steroids?


SARMs—short for “selective androgen receptor modulators”—are synthetic drugs designed to have effects similar to those of testosterone. ... Despite that, SARMs are readily available online and often marketed to bodybuilders as “legal steroids” or “steroid alternatives” or for “research only.”

*we will see the differences below*


Before we talk about the side effects of SARMs, we need to make sure everyone understands one thing:

SARMs have similar benefits as steroids, then it’s likely they will have similar side effects.


One of the more serious side effects of SARMs relates to the vision issues Andarine may produce. Nighttime blindness is a common problem among Andarine users, and it includes a strange symptom — the users may see a yellow tinge at night, and especially when they come out from a well-lit room. Still, it has been shown that at smaller dosages, this side effect doesn’t occur.


A usual problem most people have with SARMs is the suppression of natural testosterone. However, we need to note here that steroids are also suppressive. In fact, they are far more suppressive than SARMs can ever be, especially because they are often taken in large doses.

Conclusion for SARMs, the more SARMs we take, the higher the chance that we will experience consequences. Always with your doctor's advice.


STEROIDS

We all have listen about steroids but let's find out more about them.


What are the Anabolic Steroids?

Anabolic steroids are synthetic, or human-made, variations of the male sex hormone testosterone. The proper term for these compounds is anabolic-androgenic steroids. "Anabolic" refers to muscle building, and "androgenic" refers to increased male sex characteristics. Some common names for anabolic steroids are Gear, Juice, Roids, and Stackers.

Health care providers can prescribe steroids to treat hormonal issues, such as delayed puberty. Steroids can also treat diseases that cause muscle loss, such as cancer and AIDS. But some athletes and bodybuilders misuse these drugs in an attempt to boost performance or improve their physical.


Sometimes, steroids can might lead to negative mental effects, such as:


  1. paranoid (extreme, unreasonable) jealousy

  2. extreme irritability and aggression (“roid rage”)

  3. delusions—false beliefs or ideas

  4. impaired judgment

  5. mania


What are other negative health effects of anabolic steroids?

Some of them are :

  1. kidney problems or failure

  2. liver damage and tumors

  3. enlarged heart, high blood pressure, and changes in blood cholesterol, all of which increase the risk of stroke and heart attack, even in young people

  4. increased risk of blood clots



Types of anabolic steroids :

There are up to 32 types of anabolic steroid


People choose different types for different purposes:

  1. bulking steroids for building muscle

  2. performance steroids for strength and endurance

  3. cutting steroids for burning fat

Other reasons for use include healing and recovery and enhancement of metabolism.


For both medical and illegal purposes, AASs can be taken:
  1. by mouth

  2. as pellets implanted under the skin

  3. by injection

  4. through the skin as a cream or gel

Oral forms are taken by mouth. They include:
  1. Fluoxymesterone (Halotestin), or "Halo"

  2. Mesterolone (Proviron)

  3. Methandienone (Dianabol), or "Dbol"

  4. Methyltestosterone (Virilon)

  5. Mibolerone (Cheque)

  6. Oxandrolone (Anavar, Oxandrin), or "Var"

  7. Oxymetholone (Anadrol), or "Drol"

  8. Stanozolol (Winstrol), or "Winny"


Injectable forms include:
  1. Boldenone undecylenate (Equipoise), or "EQ"

  2. Methenolone enanthate (Primobolan), or "Primo"

  3. Nandrolone decanoate (Deca Durabolin), or "Deca"

  4. Nandrolone phenpropionate (Durabolin), or "NPP"

  5. Testosterone cypionate (Depotest)

  6. Testosterone enanthate (Andro-Estro)

  7. Testosterone propionate (Testex)

  8. Trenbolone acetate (Finajet), or "Tren"


*Opinion*

If you're not a pro athlete or if you don't have the amount of money to cover everything to stay healthy stay away from steroids and SARMs.



RECENT STUDY ABOUT SARMS / THE DIFFERENCE BETWEEN SARMS AND STEROIDS

A recent study that appeared in the medical journal JAMA highlighted the availability of the compounds via the internet and found that most had other substances with only 52% containing SARMs. In 2008, WADA banned SARMs, and prohibited SARMs (both in and out of competition) for all athletes, from the highest to recreational levels. SARMs are listed in the category of  Other Anabolic Agents” under section S1.2 of the WADA Prohibited List, with examples including ostarine, andarine and ligandrol.

In response to the FDA’s public announcement on SARMs, the Council for Responsible Nutrition, the trade organization for the dietary supplement industry, issued a safety alert that reiterated that SARMs are unapproved drugs and not dietary supplements. The bottom line: “SARMs should be avoided, as they can result in potentially life-threatening consequences.” From ( Adam Bible )

*Adam Bible is a veteran media professional with bylines in outlets like Men's Fitness, Muscle & Fitness, Men's Journal, Men's Health, Gear Junkie, Best Life, Road & Track, and Eat This, Not That!.


To be honest for my opinion SARMs are more popular nowadays and people think that they're 'safe' because it's legal. For me it's the exact same thing, steroids / SARMs have no difference and also they have similar side effects. Both have their risks and if you want to take that risk that's on you.



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